Introduction
Bio-Synthesis Taiwan Distribution
1. New generation LNA with higher stability
2. Effectively improve the Tm value of the probe Probe and enhance the efficiency of short sequence identification.
3. Highly specific
4. Resistant to the action of exonucleases and endonucleases
5. Suitable for PCR/qPCR/SNP/siRNA, microarray and other experiments
Features / strengths
Bridged Nucleic Acid (BNA™) is a new type of nucleotide modification. BNA™ has a bridge structure (O2', C4'-aminomethylene bridge) formed by the oxygen atom No. 2 and carbon atom No. 4 on the five-carbon sugar. This structure allows BNA™ to interact with the target gene DNA/RNA. Forms strong bonds that are more stable than ordinary DNA:DNA, DNA:RNA, RNA:RNA structures.
In experiments, using BNA™ as probe/primer/siRNA can effectively improve the hybridization ability and Tm value with the target sequence. When adding 1 BNA™, the Tm value can increase by 2 to 9 degrees C and reduce errors. Match probability.
Specification in detail
Product Information
Please email us for detailed specifications.
