Oneness and Microbio (Shanghai) signed an agreement with Cho Pharma to jointly develop glycosylation-based nucleic acid delivery technologyDec 21, 2022

Small nucleic acid medicines (eg. siRNA) have become the focus of global new drug development, and drug delivery technology is the key to the development of nucleic acid medicines. At present, the only successful technology is a nature glycan molecule called N-acetylgalactosamine (GalNAc) that is capable to deliver the medicine to the liver effectively. GalNAc proves that glycan molecules can be used as a key carrier for nucleic acid delivery. In addition to the liver, delivery technologies to other organs are urgently needed.

Oneness and Microbio (Shanghai) will collaborate with Cho Pharma, a company specialized in molecular glycosylation and will focus on development of glycosylation-based nucleic acid delivery technology. It is aimed to develop globally competitive nucleic acid medicines that can target to specific organs and achieve precision therapy.