Introduction
What are Bile Acids?
Bile acids (BAs) are a large group of metabolites synthesized in the liver from cholesterol and further modified by the gut microbiota. Beyond their essential role in lipid digestion and absorption, bile acids are also recognized as signaling molecules that regulate energy metabolism, glucose homeostasis, gut microbiota balance, and immune responses.
Why Measure Bile Acids?
In recent years, dysregulation of bile acid metabolism has been linked to various diseases, including:
●Liver diseases (fatty liver, cirrhosis, cholestasis)
●Metabolic disorders (diabetes, obesity, cardiovascular diseases)
●Gut-related diseases (inflammatory bowel disease, colorectal cancer)
Therefore, bile acid profiling is not only a valuable tool in fundamental research but is also emerging as a key approach in biomarker discovery and drug development for clinical applications.
Features / strengths
1.High-Sensitivity LC-MS/MS Platform
Enables accurate quantification of a wide range of bile acids, including:
● Primary bile acids (e.g., cholic acid, chenodeoxycholic acid)
● Secondary bile acids (e.g., deoxycholic acid, lithocholic acid)
● Conjugated bile acids (e.g., glycine- and taurine-conjugated bile acids)
2.Versatile Sample Compatibility
Applicable to blood, urine, feces, and tissue samples, with customized solutions available according to specific research needs.
3.Integrated Data & Bioinformatics Analysis
Combining metabolic profiling with bioinformatics interpretation to help researchers gain deeper insights into the metabolic interactions among the liver, gut, and microbiota.
Specification in detail
Bile acids analysis
Analytical Test Report