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Synmosa to Launch Japan’s First-in-Class IBAT Inhibitor for Chronic Constipation in Q2Jan 29, 2026

Synmosa (健喬) announced that Goofice (固腹順), an IBAT inhibitor licensed from Japan’s EA Pharma, is scheduled for Taiwan launch between April and June 2026. This marks the first-ever Ileal Bile Acid Transporter (IBAT) inhibitor available for chronic functional constipation in the region.

Market Context & Clinical Value:

  • Mechanism: The active ingredient, Elobixibat, inhibits bile acid reabsorption in the ileum, increasing bile acid levels in the colon to stimulate natural bowel movements.
  • Addressable Market: In Taiwan, over 1.4 million people seek treatment for constipation annually, with the market exceeding NT$800 million and growing at 6–8% per year.
  • Portfolio Synergy: Goofice completes Synmosa’s gastrointestinal (GI) line, which already includes established brands like Kensianning (diarrhea) and Gaviscon (GERD), positioning the group as a comprehensive leader in GI health.

Resource: 健喬引進日本EA Pharma治療慢性便秘的IBAT抑制劑 第2季上市