Lactate serves as a crucial indicator of tissue ischemia and shock. Elevated lactate levels in the blood signify inadequate oxygen supply to tissues, which may lead to multiple organ failure. Therefore, monitoring blood lactate concentration can assist physicians in early diagnosis and treatment of conditions such as shock.
A team led by Dr. Hsiao-En Tsai from National Taiwan University Hospital Hsinchu Branch has developed a real-time lactate sensor for extracorporeal circulation circuits. This sensor enables real-time monitoring of blood lactate concentration within the extracorporeal circulation circuit, aiding in the assessment of tissue ischemia and shock status, thereby facilitating clinical decision-making by healthcare teams.
Breaking free from the constraints of traditional testing methods, real-time blood lactate monitoring allows for precise assessment of the patient's condition.
Traditional blood tests require blood extraction from the patient and analysis in a laboratory, a process that is time-consuming and labor-intensive and may delay treatment. The real-time lactate sensor developed by National Taiwan University Hospital Hsinchu Branch utilizes semiconductor photolithography and inkjet printing technology to create a highly sensitive flexible sensor. By integrating multiple ion sensing electrodes, it can simultaneously detect lactate, pH, and other ions, enabling direct monitoring of blood lactate concentration within the extracorporeal circulation circuit and providing more timely and accurate information.
Flexible substrate technology enables low-cost, high reproducibility, and mass production.
This sensor is designed with a flexible substrate, allowing for mass production using semiconductor photolithography and inkjet printing technology, thereby offering advantages such as low cost, high reproducibility, and reliability. The sensor can be directly integrated into the extracorporeal circulation circuit, eliminating the need for blood sampling calibration. It can continuously monitor blood lactate trends and wirelessly transmit data to medical monitors or information systems.
Technical Features:
Wireless data transmission to medical monitors or information systems
Dr. Hsiao-En Tsai envisions that this sensor can be applied to other extracorporeal circulation circuits, such as blood dialysis circuits and cardiopulmonary machine circuits, and can expand the range of tests, achieving a more comprehensive "blood-free" testing goal. It is expected to bring innovation to emergency and critical care medicine and provide patients with higher quality medical care.
Resource (Mandarin):
血中乳酸即時監測系統 助力早期診斷休克與組織缺血
