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Bio B2BExcelsior Bio-System, Inc. 〉Rapid Test (FMD NSP Ab test)

Rapid Test (FMD NSP Ab test)

Rapid Test (FMD NSP Ab test)

The rapid test incorporates both immunoassay techniques and chromatography principles by fixing highly specific antibodies and antigens onto a nitrocellulose membrane. Colloidal gold nano-particles are used to determine the presence of antibodies or antig

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Overview
A. Preparation of Colloidal Gold :
Colloidal gold particles are the most widely used coloration agent with the following advantages :
    I. Convenient conjugation process,
    II. After synthesis, particles can be easily dispersed,
    III. Conjugation of colloidal gold and antibodies/antigen are highly stable
With a specialized chemical technique in producing the colloidal gold nano-particles, EBS is able to obtain a specific size and quality of particles. Through diligent research, the most suitable antibodies and antigens along with optimized parameters allowed EBS to develop a stable end-product.

B. Research and Develop of Rapid Test  :
The EBS R&D team developing the rapid test has diligently studied the principles of immunoassay techniques specifically relating to antibodies and antigens. Many different types of lateral immunochromatographic tests were researched, including “Direct”, “Indirect”, and “Competitive”, allowing us to select the most appropriate format for the specific rapid test kit.
 
C. Validation and Quality Control :
We validated the performance of the rapid test and tested repeatedly throughout the R&D stages to ensure the quality of the product. Multiple validation tests were performed and recorded resulting is the development of an effective, stable, and convenient product. 
    I. Interference test: Predicting and testing possible situations that may be encountered in the field relating to chemicals agents to ensure the performance and stability is not obstructed.
    II. Acceleration and Stability test: Testing the relationship between temperature and storage time on product performance and consistency, to confirm stability and shelf-life of rapid test kits.
Application
1. To detect the antibody of foot and mouth disease (FMD) virus non-structural proteins.
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