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Bio B2BiStat Biomedical Co., Ltd. 〉ZNF582 DNA Detection Kit

ZNF582 DNA Detection Kit

ZNF582 DNA Detection Kit

Oral-M
The hyper- methylation of ZNF582 was founded to have close association with oral cancer. Detection the presence of hyper-methylation of ZNF582 might provide a useful tool for early detection oral cancer.

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Overview
•Specimens of use
 Human epithelial cells (cell scrapings off  swabs)
•Recommended Real-time PCR System:
  LightCycler® 480 Instrument or Applied Biosystems® 7500 fast
•Analytical and clinical performances
  In a cross sectional study involving 267 subjects (healthy subjects and those with moderate dysplasia or worse oral lesions), the sensitivity    
  and the specificity of ZNF582 methylation were 0.85 and 0.87.
•Reference
  PLOS one:7,e41060. (2012)
  Clin Oral Invest: 18(3):801-808. (2014)
  Int. J Gynecol Cancer: 24: 928-934. (2014)
Specifications
•ISO 13485, ISO 9001, IVD-CE
Application
•ZNF582 DNA Detection Kit is a diagnostic kit for the qualitative detection of methylated ZNF582 in bisulfite-converted DNA from human cells.
•Depend on the cells used, a positive results correlated with the risk of cervical /or oral cancers. For cervical cancer, the cervical cells were collected by using of cervical brush. For oral cancer, the cells were collected by oral swab.
•ZNF582 DNA Detection Kit manufactured followed to the requirements of the directive for in vitro diagnostics (98/79/EG). Therefore it carries a CE mark. All the test results have to be evaluated by physician in combination with other clinical and laboratory findings
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